Woman's Platelet-Rich Plasma & ACell for Hair Loss

Cytokine Rich Plasma (CRP) Refined PRP

Hair Transplant & Restoration Center

Have you been suffering in silence with your hair thinning? Are you embarrassed to go out on a rainy or windy day for fear that others will be able to see your scalp? At HT&RC we can help.


Dr. Gray has been performing treatments with platelet-rich plasma for several years. Always concerned with getting the best possible results for his patients, he now offers a refined type of PRP that is rarely found in hair restoration centers across the country. This new treatment is called CRP (Cytokine Rich Plasma). Using a 5x concentration of PRP, the PRP is further refined with sonication to yield CRP. ACell provides scaffolding and healing support, which is mixed with the CRP protein growth factors. This is then administered on a strategic schedule of treatments, Dr. Gray has achieved exciting growth, healing, and retention for women facing a variety of hair loss conditions.

What is PRP?

You may have heard of PRP but didn’t really understand what it was. PRP is a powerful non-surgical treatment that uses components of a patient’s own blood to leverage the body’s natural healing abilities to fight hair loss. Its impacts are well documented, with 85% of patients seeing improvement in six months or less. Over the past year Dr. Gray began further processing the PRP to yield CRP. This CRP is offered not only as a standalone option but also includes this revolutionary treatment in every hair restoration surgery at HT&RC. CRP is also combined with ACell, an advanced wound-repair material, to accelerate healing and stimulate hair growth. Many patients have never heard of CRP, but this is the newest and by far the most effective and powerful way to deliver the protein growth factors at their highest level to the scalp. If you’ve been looking for a resource for CRP, Dr. Gray can help you evaluate your potential, administer the treatment, and monitor your results.



It is well documented that not all PRP is created equal, the focus of Dr. Gray’s PRP treatments at the Hair Transplant & Restoration Center is obtaining the maximum amount of growth factors from platelets. Dr. Gray believes the higher the level of specific growth factors, the higher the response to hair growth. Based on cutting-edge data, Dr. Gray has updated all of his technology to maximize the growth factors found in platelets which involves using a top of the line centrifuge to achieve a high platelet count, but more importantly, incorporating sonication, which is traditionally mostly used in molecular biology, biochemistry, and cell biology labs. The CRP treatment that HT&RC offers is used very few centers across the country.

Although PRP can be injected without prior activation most hair restoration physicians who use PRP activate the platelets artificially with Calcium or thrombin or trauma, and only a certain level of growth factors is released from the alpha granules in platelets. In the past, Dr. Gray has used Calcium to activate the platelets to release the growth factors. However, relatively new data showed that by processing the PRP further with sonication, there was a much more complete release of growth factors. In fact the levels were exponentially greater after sonication.

Sonication is an entirely different way to release growth factors which does not require any type of artificial "activation," AND also produces higher growth factor levels. After the centrifuge has separated components of the blood, PRP goes through sonication, and high-intensity sound waves destroy the platelet membrane which releases high levels of growth factors from alpha-granules into the plasma. This process destroys platelets, so the product produced is no longer “platelet-rich-plasma.” Instead of PRP, what remains is called CRP (Cytokine Rich Plasma) which has abundant independent growth factors, and CRP is injected into the scalp along with ACell.

Again, with the focus being on obtaining growth factors, there is an exponentially greater amount of growth factors (especially the larger growth factors like PDGF and VEGF) measured using sonication after the centrifuge.

Who is a good candidate for CRP?

If you’re among the millions of American women affected by androgenetic alopecia or age-related thinning, CRP could be a promising solution for you. Since it leverages actively growing hair, it’s important to seek CRP treatment before miniaturization becomes advanced. Like most hair medical treatments, the CRP works best before there is a lot of permanent hair loss.

Who is a good candidate for PRP/PL?


The best results can be expected by women whose hair loss can be classified as Type I or Type II (mild or moderate) on the Ludwig Scale.

Ludwig Hair Loss Scale

Strategically Timed CRP/PRP Treatments

Timing is critical in two ways – both the advancement of hair loss and the growth stage of the viable hair should be considered. You already know that CRP should be administered as early in the progression of hair loss as possible. But the timing of individual treatments is more important than most women realize.

Hair Follicles
Across the industry, the timing of CRP treatments varies widely. Thanks to his commitment to achieving the best possible results for his clients, Dr. Gray has isolated the ideal timing to maximize thickness and regrowth from CRP. It’s all about the stages of the hair growth cycle! At any one time, the majority of the hairs on your scalp are in the anagen (active growth) stage, and those hairs are primed to receive the full benefit of CRP. At the same time, a certain percentage of hairs are in the 2-to-3-month telogen (dormant) stage. Since they’re not actively growing, these strands of hair miss out on the impact of treatment. Dr. Gray has strategically synced CRP treatments to the hair growth cycle so that any follicles in the telogen phase during one treatment will have shed and there will be new actively growing follicle by the next. By delivering three CRP treatments every 6-8 weeks, Dr. Gray ensures that each and every viable follicle on your head receives treatment during the anagen phase when it’s most receptive to CRP. The CRP pushes follicles into the anagen phase and helps maintain them in that growing phase.

hair growth cycle

CRP in every hair transplant

One of the unique aspects of CRP at the Hair Transplant & Restoration Center is Dr. Gray’s inclusion of it in every FUE and FUT hair transplant procedure. By using components of the patient’s own blood, he can concentrate the body’s healing potential precisely in the area where growth is needed. CRP also helps protect hair follicles during harvesting and transplantation, so it improves the success rates of transplants. An under-appreciated benefit of combining CRP with ACell treatment is that they can be used to promote hair growth and healing – in a transplant or as a standalone treatment. Thanks to improved healing, CRP and ACell can bring as much benefit to an eyebrow transplant as to a transplant on the scalp!

What to expect during CRP treatment

Through a quick and painless process, Dr. Gray creates a sample of plasma that is highly concentrated with platelets. Blood is extracted and spun in the centrifuge to isolate the platelets that promote growth. From there, the PRP is put into a sonicator, which breaks apart the platelets using high-intensity sound waves and releases very high levels of growth factors and is now called CRP because we are left only with growth factor proteins and no longer have platelets. You will be awake throughout the treatment, but the doctor will numb your scalp so that you don’t feel any pain. ACell is combined with the CRP at the time of injection at which point Dr. Gray uses a tiny needle to inject the CRP into areas of the scalp where hair growth is needed. There’s no recovery time. CRP helps the injection sites to heal very quickly as well as Acell, an extracellular matrix with powerful skin-healing properties, which stimulates adult stem cells.

Things to be aware of:

  • Please shampoo your hair and cleanse your scalp about 24 hours before treatment.
  • Sewn-in or glued-on hairpieces should be removed before arrival.
  • There is typically no downtime directly after therapy, as the CRP helps the injection sites heal very quickly. Your scalp might feel numb for a few hours, but you can promptly resume your usual hair care routine.
  • Because of the small needle used, there are usually no visible signs of treatment on the scalp.
  • Dr. Gray will use photographs to document the change in your hair and scalp as your hair grows.
  • Although it doesn’t happen to every female, you should be aware that shedding may occur after a CRP treatment. Initial shedding should resolve on its own, and is NOT permanent. How long shedding will last varies from person to person, but there should be more benefit in the long run from high levels of growth factors in the CRP treatment than any short-term shedding you may experience.

What our patients are saying

"The pain with PRP/PL was very minimal. Dr. Grays strives very hard to minimize all discomfort. By the second treatment, just knowing what was going to happen and with his technique, virtuously it was painless. He did bacteriostatic saline, which I thought was amazing, I did not feel the needle stick in my arm from when he drew the blood. He did a topical block around my scalp, there were a few very very minimal little sticks, but it was way less, way less (pain) than receiving an injection or having blood drawn at a local facility. This was great. "

"I've noticed a fullness already (by my third treatment) on my crown where I had the PRP/PL injections done (where my areas of concern were), and I would say I first noticed this change in about two and a half to three months. A month after my first treatment, I noticed that my hair wasn't falling out as much as it was. I decided to do PRP/PL because I wanted to grow my natural hair back out as much as possible before I decided to do anything else, and there were more scientific studies to back up this treatment."

The time for suffering with hair loss is over.
Are you ready to take action? The first step toward resolution is to find out whether you’re a good candidate for CRP. CRP gets its best results in the early stages of hair loss, so don’t wait. Schedule a consultation with Dr. Gray to find out whether CRP or another medical hair loss solution can help resolve your hair loss problem. 

Get your questions answered.

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If you’re ready to explore hair restoration options, give us a call or fill out our form and discuss your hair loss with Dr. Gray. He will help you pinpoint what’s causing your hair loss and find a proven solution to stop or resolve it.

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Hair Transplant & Restoration Center

125 Plantation Centre Drive South
Building 300, Suite B
Macon, GA 31210

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