In March of this year, I updated all of my PRP equipment and invested in technology to maximize the growth factors found in platelets which involves using a top of the line centrifuge to achieve a high platelet count, but more importantly, incorporating sonication, an additional step to the process.
After the centrifuge has separated components of the blood, PRP goes through sonication, and high-intensity sound waves destroy the platelet membrane which releases high levels of growth factors from alpha-granules into the plasma, creating platelet lysate, the final product for injection.
When used for treatment under the right circumstances: moderate miniaturization, not too much permanent hair loss, I was achieving good results before with PRP, but now with Platelet Lysate under the same conditions, patients have seen a dramatic change sooner than expected.
For years, I have also included PRP as part of every hair transplant in an effort to improve existing follicles and increase the growth of the newly implanted follicles. So, when I began incorporating sonication into PRP treatments, this also included sonication in the PRP I administer during all hair transplants.
How would Platelet Lysate impact hair transplants? As patients have started coming back for followup from those March transplants where Platelet Lysate was used instead of normal PRP, there were encouraging noticeable changes. A slightly greater distinction between the previously existing miniaturizing follicles and the newly implanted follicles was most noticeable in the NW II, III, and NW IV patients.
Typically in transplants, I place the new follicles at a density of 40 grafts per sq cm, and previously combined with my old PRP protocol, this had resulted in a fluid transition. Patients may or may not need more density down the road in the non transplanted area, just depending on their situation.
As I reexamined the follicles with trichoscopy, the platelet lysate had “done its thing” and the density of areas that did not require much transplantation had dramatically increased. As the result of the effect of Platelet Lysate, those partially miniaturized follicles had sufficiently returned to a terminal follicle state.
What this has shown me is that, when using PL, a higher follicle density is essential in the newly transplanted areas. Sections of hair with partially miniaturized follicles will see a significant boost in thickness from the PL alone, and boosting the transplanted density provides hair transplant patients much denser consistency throughout all hair longterm.